OSBPL7 (oxysterol binding protein like 7)

2012-04-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
ORP7

Other Information

Locus ID:

NCBI: 114881
MIM: 606735
HGNC: 16387
Ensembl: ENSG00000006025

Variants:

dbSNP: 114881
ClinVar: 114881
TCGA: ENSG00000006025
COSMIC: OSBPL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006025ENST00000007414Q9BZF2
ENSG00000006025ENST00000392507Q9BZF2
ENSG00000006025ENST00000578461J3QSC2
ENSG00000006025ENST00000579728J3QLK7

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Bile acid and bile salt metabolismREACTOMER-HSA-194068
Synthesis of bile acids and bile saltsREACTOMER-HSA-192105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
217634552012Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
216691982011OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability.2

Citation

Dessen P

OSBPL7 (oxysterol binding protein like 7)

Atlas Genet Cytogenet Oncol Haematol. 2012-04-01

Online version: http://atlasgeneticsoncology.org/gene/52681/osbpl7