APOBEC2 (apolipoprotein B mRNA editing enzyme catalytic subunit 2)

2012-06-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
ARCD1,ARP1

Other Information

Locus ID:

NCBI: 10930
MIM: 604797
HGNC: 605
Ensembl: ENSG00000124701

Variants:

dbSNP: 10930
ClinVar: 10930
TCGA: ENSG00000124701
COSMIC: APOBEC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124701ENST00000244669Q9Y235

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
mRNA EditingREACTOMER-HSA-75072
mRNA Editing: C to U ConversionREACTOMER-HSA-72200
Formation of the EditosomeREACTOMER-HSA-75094

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
171870542007The APOBEC-2 crystal structure and functional implications for the deaminase AID.104
189748422008Gender differences in genetic risk profiles for cardiovascular disease.33
214691432012Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.18
199111242009APOBEC deaminases-mutases with defensive roles for immunity.14
201388412010Microarray analysis of tonsils in immunoglobulin A nephropathy patients.6

Citation

Dessen P

APOBEC2 (apolipoprotein B mRNA editing enzyme catalytic subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52755/apobec2-(apolipoprotein-b-mrna-editing-enzyme-catalytic-subunit-2)