IPO13 (importin 13)

2012-10-01  

Identity

HGNC
IPO13
LOCATION
1p34.1
LOCUSID
9670
ALIAS
IMP13,KAP13,LGL2,RANBP13
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9670
MIM: 610411
HGNC: 16853
Ensembl: ENSG00000117408

Variants:

dbSNP: 9670
ClinVar: 9670
TCGA: ENSG00000117408
COSMIC: IPO13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117408ENST00000372339Q5T4X2
ENSG00000117408ENST00000372343O94829

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366722142023The Nuclear Transporter Importin 13 Can Regulate Stress-Induced Cell Death through the Clusterin/KU70 Axis.0
366722142023The Nuclear Transporter Importin 13 Can Regulate Stress-Induced Cell Death through the Clusterin/KU70 Axis.0
346255402021Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response.9
346255402021Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response.9
330823052020Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation.4
330823052020Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation.4
296661592018Extensive Identification and In-depth Validation of Importin 13 Cargoes.18
297002842018Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract.14
300458752018PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function.6
296661592018Extensive Identification and In-depth Validation of Importin 13 Cargoes.18
297002842018Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract.14
300458752018PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function.6
289688292017Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.4
289688292017Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.4
234355622013Structural basis for the nuclear export activity of Importin13.22

Citation

Dessen P

IPO13 (importin 13)

Atlas Genet Cytogenet Oncol Haematol. 2012-10-01

Online version: http://atlasgeneticsoncology.org/gene/52899/tumors-explorer/meetings/favicon/favicon-32x32.png