ANKRD28 (ankyrin repeat domain 28)

2012-11-01  

Identity

HGNC
ANKRD28
LOCATION
3p25.1
LOCUSID
23243
ALIAS
CFAP79,FAP79,PITK,PPP1R65
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23243
MIM: 611122
HGNC: 29024
Ensembl: ENSG00000206560

Variants:

dbSNP: 23243
ClinVar: 23243
TCGA: ENSG00000206560
COSMIC: ANKRD28

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000206560ENST00000399451O15084
ENSG00000206560ENST00000399451A0A024R2G8
ENSG00000206560ENST00000412318O15084
ENSG00000206560ENST00000412318A0A024R2G8
ENSG00000206560ENST00000439830F8WDU2
ENSG00000206560ENST00000451422B4DIW9
ENSG00000206560ENST00000624145O15084

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991

References

Pubmed IDYearTitleCitations
191185472009Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.13
259025382015Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.10
270263982016BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28.5
165646772006PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K.4
170231422007Dual kinase-mediated regulation of PITK by CaMKII and GSK3.3
305723912018[Effect of hnRNP K and its interaction with HPV16 on cervical intraepithelial neoplasia].0

Citation

Dessen P

ANKRD28 (ankyrin repeat domain 28)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52969/ankrd28-(ankyrin-repeat-domain-28)