DAZAP1 (DAZ associated protein 1)

2012-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 26528
MIM: 607430
HGNC: 2683
Ensembl: ENSG00000071626

Variants:

dbSNP: 26528
ClinVar: 26528
TCGA: ENSG00000071626
COSMIC: DAZAP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071626ENST00000233078Q96EP5
ENSG00000071626ENST00000233078A0A0S2Z569
ENSG00000071626ENST00000336761Q96EP5
ENSG00000071626ENST00000587079K7EK33
ENSG00000071626ENST00000592453K7EQ02
ENSG00000071626ENST00000592522K7EQ55

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373491142023NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction.0
373491142023NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction.0
350919972022DAZAP1 overexpression promotes growth of HCC cell lines: a primary study using CEUS.1
362425902022DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway.2
350919972022DAZAP1 overexpression promotes growth of HCC cell lines: a primary study using CEUS.1
362425902022DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway.2
333588592021RNA binding protein DAZAP1 promotes HCC progression and regulates ferroptosis by interacting with SLC7A11 mRNA.39
333588592021RNA binding protein DAZAP1 promotes HCC progression and regulates ferroptosis by interacting with SLC7A11 mRNA.39
323087632020Starvation-induced suppression of DAZAP1 by miR-10b integrates splicing control into TSC2-regulated oncogenic autophagy in esophageal squamous cell carcinoma.16
323087632020Starvation-induced suppression of DAZAP1 by miR-10b integrates splicing control into TSC2-regulated oncogenic autophagy in esophageal squamous cell carcinoma.16
295058342018Specific intron-dependent loading of DAZAP1 onto the cox6c transcript suppresses pre-mRNA splicing efficacy and induces cell growth retardation.5
295058342018Specific intron-dependent loading of DAZAP1 onto the cox6c transcript suppresses pre-mRNA splicing efficacy and induces cell growth retardation.5
244520132014The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.35
244520132014The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.35
231113262012Transcription-dependent nuclear localization of DAZAP1 requires an N-terminal signal.2

Citation

Dessen P

DAZAP1 (DAZ associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52989/cancer-prone-explorer/js/lib/favicon/favicon-32x32.png