DLGAP3 (DLG associated protein 3)

2012-11-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
DAP3,SAPAP3
FUSION GENES

Other Information

Locus ID:

NCBI: 58512
MIM: 611413
HGNC: 30368
Ensembl: ENSG00000116544

Variants:

dbSNP: 58512
ClinVar: 58512
TCGA: ENSG00000116544
COSMIC: DLGAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116544ENST00000235180O95886
ENSG00000116544ENST00000373347O95886

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190964512009Multiple rare SAPAP3 missense variants in trichotillomania and OCD.65
190512372009Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.62
190512372009Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.62
211845902011Family-based genetic association study of DLGAP3 in Tourette Syndrome.29
212952252011Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population.21
219900082011Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms.15
234146532013Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.10

Citation

Dessen P

DLGAP3 (DLG associated protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52994/dlgap3-(dlg-associated-protein-3)