PHF20L1 (PHD finger protein 20 like 1)

2012-11-01  

Identity

HGNC
PHF20L1
LOCATION
8q24.22
LOCUSID
51105
ALIAS
CGI-72,TDRD20B,URLC1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51105
HGNC: 24280
Ensembl: ENSG00000129292

Variants:

dbSNP: 51105
ClinVar: 51105
TCGA: ENSG00000129292
COSMIC: PHF20L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129292ENST00000220847A0A0A0MQS0
ENSG00000129292ENST00000337920A8MW92
ENSG00000129292ENST00000395376A8MXR8
ENSG00000129292ENST00000395379A8MUE8
ENSG00000129292ENST00000395386A8MW92
ENSG00000129292ENST00000395390F8W9L8
ENSG00000129292ENST00000460236H0YDF7
ENSG00000129292ENST00000485595A0A0D9SG14
ENSG00000129292ENST00000486199E9PM57
ENSG00000129292ENST00000521038H0YC05
ENSG00000129292ENST00000522580E5RK91
ENSG00000129292ENST00000622263A8MW92

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384111162024Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.0
384111162024Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.0
353570962022PHF20L1 mediates PAX2 expression to promote angiogenesis and liver metastasis in colorectal cancer through regulating HIC1.1
353570962022PHF20L1 mediates PAX2 expression to promote angiogenesis and liver metastasis in colorectal cancer through regulating HIC1.1
338474742021An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer.2
338474742021An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer.2
324946082020PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.19
324946082020PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.19
293583312018LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.18
300898522018PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes.5
293583312018LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.18
300898522018PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes.5
288412142017Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.14
288412142017Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.14
265888622016An integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancer.17

Citation

Dessen P

PHF20L1 (PHD finger protein 20 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/53032/gene-fusions-explorer/js/favicon/favicon-16x16.png