ZC3H12D (zinc finger CCCH-type containing 12D)

2012-11-01  

Identity

HGNC
ZC3H12D
LOCATION
6q25.1
LOCUSID
340152
ALIAS
C6orf95,MCPIP4,TFL,dJ281H8.1,p34
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 340152
MIM: 611106
HGNC: 21175
Ensembl: ENSG00000178199

Variants:

dbSNP: 340152
ClinVar: 340152
TCGA: ENSG00000178199
COSMIC: ZC3H12D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178199ENST00000409806A2A288
ENSG00000178199ENST00000409948B7ZBA4
ENSG00000178199ENST00000458251H0Y4Y6

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
181785542008A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.82
261345602015Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation.3
220368052012The putative tumor suppressor Zc3h12d modulates toll-like receptor signaling in macrophages.0
260597552015ZC3H12D attenuated inflammation responses by reducing mRNA stability of proinflammatory genes.0
274728302017Intact NYN/PIN-Like Domain is Crucial for the Degradation of Inflammation-Related Transcripts by ZC3H12D.0

Citation

Dessen P

ZC3H12D (zinc finger CCCH-type containing 12D)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/53061/zc3h12d-(zinc-finger-ccch-type-containing-12d)