AKR1E2 (aldo-keto reductase family 1 member E2)

2012-12-01  

Identity

HGNC
AKR1E2
LOCATION
10p15.1
LOCUSID
83592
ALIAS
AKR1CL2,AKRDC1,HTSP1,LoopADR,TAKR,hTSP,htAKR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83592
MIM: 617451
HGNC: 23437
Ensembl: ENSG00000165568

Variants:

dbSNP: 83592
ClinVar: 83592
TCGA: ENSG00000165568
COSMIC: AKR1E2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165568ENST00000298375Q96JD6
ENSG00000165568ENST00000334019Q96JD6
ENSG00000165568ENST00000345253Q96JD6
ENSG00000165568ENST00000463345Q96JD6
ENSG00000165568ENST00000474119G3V1C1
ENSG00000165568ENST00000487985H0YCI2
ENSG00000165568ENST00000525572H0YDE8
ENSG00000165568ENST00000532248Q96JD6
ENSG00000165568ENST00000533295E9PK93

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
151180782004Characterization of htAKR, a novel gene product in the aldo-keto reductase family specifically expressed in human testis.5
151180782004Characterization of htAKR, a novel gene product in the aldo-keto reductase family specifically expressed in human testis.5

Citation

Dessen P

AKR1E2 (aldo-keto reductase family 1 member E2)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53068/teaching-explorer/js/lib/favicon/favicon-16x16.png