EXO5 (exonuclease 5)

2013-01-01  

Identity

HGNC
LOCATION
1p34.2
LOCUSID
ALIAS
C1orf176,DEM1,Exo
FUSION GENES

Other Information

Locus ID:

NCBI: 64789
MIM: 618601
HGNC: 26115
Ensembl: ENSG00000164002

Variants:

dbSNP: 64789
ClinVar: 64789
TCGA: ENSG00000164002
COSMIC: EXO5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164002ENST00000296380Q9H790
ENSG00000164002ENST00000358527Q9H790
ENSG00000164002ENST00000372703Q9H790
ENSG00000164002ENST00000415550X6RK18
ENSG00000164002ENST00000418186X6RCL8
ENSG00000164002ENST00000419161X6RCY3
ENSG00000164002ENST00000420209X6RF29
ENSG00000164002ENST00000432259X6RLK1
ENSG00000164002ENST00000443729X6RCY3

Expression (GTEx)

0
1
2
3
4
5
6
7

References

Pubmed IDYearTitleCitations
341977372021EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.21
341977372021EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.21
316160622020Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis.8
316160622020Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis.8
297614802018Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.14
297614802018Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.14
230957562012Human exonuclease 5 is a novel sliding exonuclease required for genome stability.14
230957562012Human exonuclease 5 is a novel sliding exonuclease required for genome stability.14

Citation

Dessen P

EXO5 (exonuclease 5)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53140/gene-fusions-explorer/js/css/lib/dataTables.bootstrap.min.css