EVA1A (eva-1 homolog A, regulator of programmed cell death)

2013-05-01  

Identity

HGNC
EVA1A
LOCATION
2p12
LOCUSID
84141
ALIAS
FAM176A,TMEM166
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84141
HGNC: 25816
Ensembl: ENSG00000115363

Variants:

dbSNP: 84141
ClinVar: 84141
TCGA: ENSG00000115363
COSMIC: EVA1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115363ENST00000233712Q9H8M9
ENSG00000115363ENST00000393913Q9H8M9
ENSG00000115363ENST00000410010B8ZZF5
ENSG00000115363ENST00000410071Q9H8M9
ENSG00000115363ENST00000410113Q9H8M9
ENSG00000115363ENST00000432649C9J5M4
ENSG00000115363ENST00000452003C9JX09

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387343022024Increased TMEM166 Level in Patients with Postoperative Stroke after Carotid Endarterectomy.0
387343022024Increased TMEM166 Level in Patients with Postoperative Stroke after Carotid Endarterectomy.0
367945852023EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy.3
367945852023EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy.3
360781152022The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().4
362731222022Down-regulation of EVA1A by miR-103a-3p promotes hepatocellular carcinoma cells proliferation and migration.5
360781152022The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().4
362731222022Down-regulation of EVA1A by miR-103a-3p promotes hepatocellular carcinoma cells proliferation and migration.5
319770092021Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b.12
330065342021Transmembrane Protein 166 and its Significance.2
332003772021TMEM166 inhibits cell proliferation, migration and invasion in hepatocellular carcinoma via upregulating TP53.8
335567102021Eva1a inhibits NLRP3 activation to reduce liver ischemia-reperfusion injury via inducing autophagy in kupffer cells.17
319770092021Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b.12
330065342021Transmembrane Protein 166 and its Significance.2
332003772021TMEM166 inhibits cell proliferation, migration and invasion in hepatocellular carcinoma via upregulating TP53.8

Citation

Dessen P

EVA1A (eva-1 homolog A, regulator of programmed cell death)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53273/js/lib/js/js/template.js