ACP3 (acid phosphatase 3)

2013-06-01  

Identity

HGNC
ACP3
LOCATION
3q22.1
LOCUSID
55
ALIAS
5-NT,ACP-3,ACPP,TM-PAP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55
MIM: 171790
HGNC: 125
Ensembl: ENSG00000014257

Variants:

dbSNP: 55
ClinVar: 55
TCGA: ENSG00000014257
COSMIC: ACP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000014257ENST00000336375P15309
ENSG00000014257ENST00000351273P15309
ENSG00000014257ENST00000475741P15309
ENSG00000014257ENST00000495911E9PFE6
ENSG00000014257ENST00000507647H0Y8T3

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
196360172009Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer.89
189405922008Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine.77
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
220901092012Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection.49
194036772009Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.40
176388632007Prostatic acid phosphatase is not a prostate specific target.39
238978102013Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.31
214875252011Prostatic acid phosphatase expression in human tissues.24
204983732010Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth.22
223549632012Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide.20

Citation

Dessen P

ACP3 (acid phosphatase 3)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53343/acp3