MAP3K19 (mitogen-activated protein kinase kinase kinase 19)

2013-06-01  

Identity

HGNC
LOCATION
2q21.3
LOCUSID
ALIAS
RCK,YSK4
FUSION GENES

Other Information

Locus ID:

NCBI: 80122
HGNC: 26249
Ensembl: ENSG00000176601

Variants:

dbSNP: 80122
ClinVar: 80122
TCGA: ENSG00000176601
COSMIC: MAP3K19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176601ENST00000358371Q56UN5
ENSG00000176601ENST00000375844Q56UN5
ENSG00000176601ENST00000375845Q56UN5
ENSG00000176601ENST00000392915Q56UN5
ENSG00000176601ENST00000392917Q56UN5
ENSG00000176601ENST00000392918Q56UN5
ENSG00000176601ENST00000414343C9JGQ2
ENSG00000176601ENST00000437365H7C041
ENSG00000176601ENST00000637841A0A1B0GTF4
ENSG00000176601ENST00000656750A0A590UJV9
ENSG00000176601ENST00000662522A0A590UJK1

Expression (GTEx)

0
5
10
15

References

Pubmed IDYearTitleCitations
323580592020The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells.12
323580592020The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells.12
279359622016MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction.16
279359622016MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction.16

Citation

Dessen P

MAP3K19 (mitogen-activated protein kinase kinase kinase 19)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53350/meetings/favicon/apple-touch-icon.png