FIGNL1 (fidgetin like 1)

2013-09-01  

Identity

HGNC
FIGNL1
LOCATION
7p12.2
LOCUSID
63979
ALIAS
-

Other Information

Locus ID:

NCBI: 63979
MIM: 615383
HGNC: 13286
Ensembl: ENSG00000132436

Variants:

dbSNP: 63979
ClinVar: 63979
TCGA: ENSG00000132436
COSMIC: FIGNL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132436ENST00000356889Q6PIW4
ENSG00000132436ENST00000395556Q6PIW4
ENSG00000132436ENST00000419119Q6PIW4
ENSG00000132436ENST00000420829C9JTG6
ENSG00000132436ENST00000422854C9JHJ4
ENSG00000132436ENST00000433017Q6PIW4
ENSG00000132436ENST00000435566C9JSC4
ENSG00000132436ENST00000436590C9JKI6
ENSG00000132436ENST00000440350C9JTB2
ENSG00000132436ENST00000448788C9JP37
ENSG00000132436ENST00000611938Q6PIW4
ENSG00000132436ENST00000613602Q6PIW4
ENSG00000132436ENST00000615084Q6PIW4
ENSG00000132436ENST00000617389Q6PIW4

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379297332024FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR.0
382868052024FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress.1
385976692024Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation.1
379297332024FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR.0
382868052024FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress.1
385976692024Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation.1
378911732023FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.2
378911732023FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.2
357916742022FIGNL1 is a potential biomarker of cisplatin resistance in non-small cell lung cancer.1
357916742022FIGNL1 is a potential biomarker of cisplatin resistance in non-small cell lung cancer.1
333679322021FIGNL1 promotes non‑small cell lung cancer cell proliferation.2
333679322021FIGNL1 promotes non‑small cell lung cancer cell proliferation.2
309267762019Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase.22
315410152019FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.2
309267762019Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase.22

Citation

Dessen P

FIGNL1 (fidgetin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53507/favicon/js/lib/jquery-3.5.1.min.js