TENT4B (terminal nucleotidyltransferase 4B)

2014-01-01  

Identity

HGNC
TENT4B
LOCATION
16q12.1
LOCUSID
64282
ALIAS
PAPD5,TRF4-2,TUT3

Other Information

Locus ID:

NCBI: 64282
MIM: 605540
HGNC: 30758
Ensembl: ENSG00000121274

Variants:

dbSNP: 64282
ClinVar: 64282
TCGA: ENSG00000121274
COSMIC: TENT4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121274ENST00000357464E9PC61
ENSG00000121274ENST00000436909Q8NDF8
ENSG00000121274ENST00000561678G4U4J3
ENSG00000121274ENST00000561678H3BQM0

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
TRAMP complexKEGGhsa_M00393
TRAMP complexKEGGM00393

References

Pubmed IDYearTitleCitations
358677482022The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.10
358677482022The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.10
324514882020Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing.29
325592912020Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.18
326987572020Long noncoding RNA CASC2 inhibits ox-LDL-mediated vascular smooth muscle cells proliferation and migration via the regulation of miR-532-3p/PAPD5.5
324514882020Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing.29
325592912020Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.18
326987572020Long noncoding RNA CASC2 inhibits ox-LDL-mediated vascular smooth muscle cells proliferation and migration via the regulation of miR-532-3p/PAPD5.5
309300562019Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.35
309300562019Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.35
300263172018Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.66
300263172018Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.66
283837162017Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism.9
283837162017Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism.9
274348182016Interaction properties of human TRAMP-like proteins and their role in pre-rRNA 5'ETS turnover.19

Citation

Dessen P

TENT4B (terminal nucleotidyltransferase 4B)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53652/case-report-explorer/js/lib/all.min.js