ARL4A (ADP ribosylation factor like GTPase 4A)

2014-06-01  

Identity

HGNC
ARL4A
LOCATION
7p21.3
LOCUSID
10124
ALIAS
ARL4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10124
MIM: 604786
HGNC: 695
Ensembl: ENSG00000122644

Variants:

dbSNP: 10124
ClinVar: 10124
TCGA: ENSG00000122644
COSMIC: ARL4A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122644ENST00000356797P40617
ENSG00000122644ENST00000356797A0A024R9Z2
ENSG00000122644ENST00000396662P40617
ENSG00000122644ENST00000396662A0A024R9Z2
ENSG00000122644ENST00000396663P40617
ENSG00000122644ENST00000396663A0A024R9Z2
ENSG00000122644ENST00000396664P40617
ENSG00000122644ENST00000396664A0A024R9Z2
ENSG00000122644ENST00000404894P40617
ENSG00000122644ENST00000404894A0A024R9Z2
ENSG00000122644ENST00000439721C9J7Q9
ENSG00000122644ENST00000651779P40617
ENSG00000122644ENST00000651779A0A024R9Z2

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
173980952007The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.47
219307032011The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.19
221594192011ARL4A acts with GCC185 to modulate Golgi complex organization.14
182409262008Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.5
304277592019ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation.1

Citation

Dessen P

ARL4A (ADP ribosylation factor like GTPase 4A)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53967/arl4a-(adp-ribosylation-factor-like-gtpase-4a)