ANP32E (acidic nuclear phosphoprotein 32 family member E)

2014-08-01  

Identity

HGNC
LOCATION
1q21.2
LOCUSID
ALIAS
LANP-L,LANPL
FUSION GENES

Other Information

Locus ID:

NCBI: 81611
MIM: 609611
HGNC: 16673
Ensembl: ENSG00000143401

Variants:

dbSNP: 81611
ClinVar: 81611
TCGA: ENSG00000143401
COSMIC: ANP32E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143401ENST00000369114Q5TB19
ENSG00000143401ENST00000369115Q5TB25
ENSG00000143401ENST00000436748Q9BTT0
ENSG00000143401ENST00000532744E9PPH5
ENSG00000143401ENST00000533654E9PLC4
ENSG00000143401ENST00000534220E9PI45
ENSG00000143401ENST00000534437H0YCE2
ENSG00000143401ENST00000583931Q9BTT0
ENSG00000143401ENST00000616917Q9BTT0
ENSG00000143401ENST00000629042Q5TB25

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
244635112014ANP32E is a histone chaperone that removes H2A.Z from chromatin.75
246138782014Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z.33
260342802015Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair.29
282206272017Downregulation of miRNA-141 in breast cancer cells is associated with cell migration and invasion: involvement of ANP32E targeting.18
124387412002Molecular cloning and characterization of a novel human gene (ANP32E alias LANPL) from human fetal brain.5
296335132018ANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.4
303290262019ANP32E, a Protein Involved in Steroid-Refractoriness in Ulcerative Colitis, Identified by a Systems Biology Approach.2

Citation

Dessen P

ANP32E (acidic nuclear phosphoprotein 32 family member E)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54129/anp32e