BET1L (Bet1 golgi vesicular membrane trafficking protein like)

2014-08-01  

Identity

HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
BET1L1,GOLIM3,GS15,HSPC197
FUSION GENES

Other Information

Locus ID:

NCBI: 51272
MIM: 615417
HGNC: 19348
Ensembl: ENSG00000177951

Variants:

dbSNP: 51272
ClinVar: 51272
TCGA: ENSG00000177951
COSMIC: BET1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177951ENST00000325147A0A0C4DH16
ENSG00000177951ENST00000332865H7BXT7
ENSG00000177951ENST00000382762Q9NYM9
ENSG00000177951ENST00000410108B8ZZS0
ENSG00000177951ENST00000486280E9PQJ6
ENSG00000177951ENST00000529614E9PHY4

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
123887522002GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus.50
236046782013BET1L and TNRC6B associate with uterine fibroid risk among European Americans.17
238925402013Variants in BET1L and TNRC6B associate with increasing fibroid volume and fibroid type among European Americans.15
273854022016COG lobe B sub-complex engages v-SNARE GS15 and functions via regulated interaction with lobe A sub-complex.11
297435412018Association of BET1L and TNRC6B with uterine leiomyoma risk and its relevant clinical features in Han Chinese population.1
312754552019Replication of GWAS Loci Revealed an Increased Risk of BET1L and H19 Polymorphisms with Intracranial Aneurysm.0

Citation

Dessen P

BET1L (Bet1 golgi vesicular membrane trafficking protein like)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54154/bet1l-(bet1-golgi-vesicular-membrane-trafficking-protein-like)