ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains)

2014-08-01  

Identity

HGNC
ILRUN
LOCATION
6p21.31
LOCUSID
64771
ALIAS
C6orf106,FP852,dJ391O22.4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64771
MIM: 612217
HGNC: 21215
Ensembl: ENSG00000196821

Variants:

dbSNP: 64771
ClinVar: 64771
TCGA: ENSG00000196821
COSMIC: ILRUN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196821ENST00000374021Q5TH58
ENSG00000196821ENST00000374023Q9H6K1
ENSG00000196821ENST00000374023A0A024RCW2
ENSG00000196821ENST00000374026Q9H6K1

References

Pubmed IDYearTitleCitations
192660772009Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.48
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.19
190594772009Enhancement of PPAR-beta activity by repetitive low-grade H(2)O(2) stress protects human umbilical vein endothelial cells from subsequent oxidative stress-induced apoptosis.7
208462172010Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.7
259532612015A novel biomarker C6orf106 promotes the malignant progression of breast cancer.5
306770292019Genetic architecture of human thinness compared to severe obesity.5
180035972008PPARalpha and PPARbeta are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line.4
257369252015C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.4
187936122008Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor beta in HEK293 cells.2
303111082019C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.2

Citation

Dessen P

ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54178/ilrun