MOBP (myelin associated oligodendrocyte basic protein)

2014-08-01  

Identity

HGNC
LOCATION
3p22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 4336
MIM: 600948
HGNC: 7189
Ensembl: ENSG00000168314

Variants:

dbSNP: 4336
ClinVar: 4336
TCGA: ENSG00000168314
COSMIC: MOBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168314ENST00000311042Q13875
ENSG00000168314ENST00000383754Q13875
ENSG00000168314ENST00000383754A0A0S2Z3W1
ENSG00000168314ENST00000415443Q13875
ENSG00000168314ENST00000415443A0A0S2Z3W1
ENSG00000168314ENST00000420739Q13875
ENSG00000168314ENST00000420739A0A024R2N4
ENSG00000168314ENST00000424090Q13875
ENSG00000168314ENST00000424090A0A024R2N4
ENSG00000168314ENST00000428261Q13875
ENSG00000168314ENST00000428261A0A0S2Z3W1
ENSG00000168314ENST00000436143C9JLT8
ENSG00000168314ENST00000441980Q13875
ENSG00000168314ENST00000441980A0A024R2N4
ENSG00000168314ENST00000442631Q13875
ENSG00000168314ENST00000442631A0A024R2P3
ENSG00000168314ENST00000447324Q13875
ENSG00000168314ENST00000447324A0A0S2Z3W1
ENSG00000168314ENST00000451925C9JAR7
ENSG00000168314ENST00000452959Q13875
ENSG00000168314ENST00000452959A0A0S2Z3W1

Expression (GTEx)

0
500
1000
1500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164778930creatineChemicalClinicalAnnotationassociatedPD31624333
PA443332Amyotrophic Lateral SclerosisDiseaseClinicalAnnotationassociatedPD31624333

References

Pubmed IDYearTitleCitations
274553482016Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.96
150096772004Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin.81
260779512015Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.52
179641172008Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.41
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
231168762013An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease.15
249948432014Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.7
311839262019Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies.0

Citation

Dessen P

MOBP (myelin associated oligodendrocyte basic protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54464/mobp