RPS16 (ribosomal protein S16)

2014-08-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
S16
FUSION GENES

Other Information

Locus ID:

NCBI: 6217
MIM: 603675
HGNC: 10396
Ensembl: ENSG00000105193

Variants:

dbSNP: 6217
ClinVar: 6217
TCGA: ENSG00000105193
COSMIC: RPS16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105193ENST00000251453P62249
ENSG00000105193ENST00000339471Q6IPX4
ENSG00000105193ENST00000599539M0R3H0
ENSG00000105193ENST00000599705M0R1M5
ENSG00000105193ENST00000601655M0R210
ENSG00000105193ENST00000602153M0QX76

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000
4500
5000

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
Formation of the ternary complex, and subsequently, the 43S complexREACTOMER-HSA-72695
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SREACTOMER-HSA-72662
Translation initiation complex formationREACTOMER-HSA-72649
Ribosomal scanning and start codon recognitionREACTOMER-HSA-72702
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
358731502022MicroRNA let-7 Suppresses Influenza A Virus Infection by Targeting RPS16 and Enhancing Type I Interferon Response.3
358731502022MicroRNA let-7 Suppresses Influenza A Virus Infection by Targeting RPS16 and Enhancing Type I Interferon Response.3
341546572021USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells.24
341546572021USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells.24
288277312017MicroRNA-7641 is a regulator of ribosomal proteins and a promising targeting factor to improve the efficacy of cancer therapy.25
288277312017MicroRNA-7641 is a regulator of ribosomal proteins and a promising targeting factor to improve the efficacy of cancer therapy.25
258933432015Dysregulated COL3A1 and RPL8, RPS16, and RPS23 in Disc Degeneration Revealed by Bioinformatics Methods.10
258933432015Dysregulated COL3A1 and RPL8, RPS16, and RPS23 in Disc Degeneration Revealed by Bioinformatics Methods.10
197732622010Diamond-Blackfan anemia: genotype-phenotype correlations in Italian patients with RPL5 and RPL11 mutations.40
201988632010[Human ribosomal protein S16 inhibites excision of the first intron from its own].0
197732622010Diamond-Blackfan anemia: genotype-phenotype correlations in Italian patients with RPL5 and RPL11 mutations.40
201988632010[Human ribosomal protein S16 inhibites excision of the first intron from its own].0
195590692009Interactions of human ribosomal proteins S16 and S5 with an 18S rRNA fragment containing their binding sites.5
195590692009Interactions of human ribosomal proteins S16 and S5 with an 18S rRNA fragment containing their binding sites.5
183181212007[Binding of human ribosomal protein S16 with the 18S rRNA fragment 1203-1236/1521-1698].1

Citation

Dessen P

RPS16 (ribosomal protein S16)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54593/gene-fusions/css/card-gene.css