SKA2 (spindle and kinetochore associated complex subunit 2)

2014-08-01  

Identity

HGNC
LOCATION
17q22
LOCUSID
ALIAS
FAM33A
FUSION GENES

Other Information

Locus ID:

NCBI: 348235
MIM: 616674
HGNC: 28006
Ensembl: ENSG00000182628

Variants:

dbSNP: 348235
ClinVar: 348235
TCGA: ENSG00000182628
COSMIC: SKA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182628ENST00000330137Q8WVK7
ENSG00000182628ENST00000437036Q8WVK7
ENSG00000182628ENST00000578105J3KTC5
ENSG00000182628ENST00000578519J3QS74
ENSG00000182628ENST00000580541J3KRW9
ENSG00000182628ENST00000581068J3KRZ0
ENSG00000182628ENST00000583380J3KSP0
ENSG00000182628ENST00000583976J3QKN8
ENSG00000182628ENST00000584089J3QL03

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372041422024The rs7208505 Polymorphism and Differential Expression of the SKA2 Gene in the Prefrontal Cortex of Suicide Victims from the Mexican Population.0
385280042024SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.0
372041422024The rs7208505 Polymorphism and Differential Expression of the SKA2 Gene in the Prefrontal Cortex of Suicide Victims from the Mexican Population.0
385280042024SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.0
378454952023Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD.0
378454952023Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD.0
323640832021The Shift of HbF to HbA under Influence of SKA2 Gene; A Possible Link between Cortisol and Hematopoietic Maturation in Term and Preterm Newborns.0
332448652021Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR-140-3p/SKA2 axis.26
334779432021HEDGEHOG/GLI Modulates the PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas.3
339810102021Resting mononuclear cell NR3C1 and SKA2 expression levels predict blunted cortisol reactivity to combat training stress among elite army cadets exposed to childhood adversity.1
340455122021Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma.5
323640832021The Shift of HbF to HbA under Influence of SKA2 Gene; A Possible Link between Cortisol and Hematopoietic Maturation in Term and Preterm Newborns.0
332448652021Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR-140-3p/SKA2 axis.26
334779432021HEDGEHOG/GLI Modulates the PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas.3
339810102021Resting mononuclear cell NR3C1 and SKA2 expression levels predict blunted cortisol reactivity to combat training stress among elite army cadets exposed to childhood adversity.1

Citation

Dessen P

SKA2 (spindle and kinetochore associated complex subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54621/deep-insight-explorer/js/web-card-_common.js