TXNDC11 (thioredoxin domain containing 11)

2014-08-01  

Identity

HGNC
LOCATION
16p13.13
LOCUSID
ALIAS
EFP1
FUSION GENES

Other Information

Locus ID:

NCBI: 51061
MIM: 617792
HGNC: 28030
Ensembl: ENSG00000153066

Variants:

dbSNP: 51061
ClinVar: 51061
TCGA: ENSG00000153066
COSMIC: TXNDC11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153066ENST00000283033Q6PKC3
ENSG00000153066ENST00000356957Q6PKC3
ENSG00000153066ENST00000571882I3L2Z6
ENSG00000153066ENST00000575591I3L0Q4
ENSG00000153066ENST00000576969I3L1A5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA444552HypertensionDiseaseClinicalAnnotationassociatedPD
PA449899hydrochlorothiazideChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
376861742023High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.0
376861742023High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.0
361522282022Expression analysis and functional characterization of thioredoxin domain-containing protein 11.1
361522282022Expression analysis and functional characterization of thioredoxin domain-containing protein 11.1
320655822020EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.16
320655822020EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.16
155617112005Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.27
155617112005Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.27

Citation

Dessen P

TXNDC11 (thioredoxin domain containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54741/case-report-explorer/css/lib/js/lib/all.min.js