ZFYVE19 (zinc finger FYVE-type containing 19)

2014-08-01  

Identity

HGNC
ZFYVE19
LOCATION
15q15.1
LOCUSID
84936
ALIAS
ANCHR,MPFYVE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84936
HGNC: 20758
Ensembl: ENSG00000166140

Variants:

dbSNP: 84936
ClinVar: 84936
TCGA: ENSG00000166140
COSMIC: ZFYVE19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166140ENST00000299173Q96K21
ENSG00000166140ENST00000336455Q96K21
ENSG00000166140ENST00000355341Q96K21
ENSG00000166140ENST00000561617H3BN64
ENSG00000166140ENST00000561768H3BS07
ENSG00000166140ENST00000564258Q96K21
ENSG00000166140ENST00000566407H3BRM1
ENSG00000166140ENST00000566767H3BUW6
ENSG00000166140ENST00000567756H3BVF5
ENSG00000166140ENST00000568062H3BP54
ENSG00000166140ENST00000569057H3BSF5
ENSG00000166140ENST00000570108H3BRF9

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
388161932024ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death.0
388161932024ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death.0
327371362021Biallelic loss-of-function ZFYVE19 mutations are associated with congenital hepatic fibrosis, sclerosing cholangiopathy and high-GGT cholestasis.9
327371362021Biallelic loss-of-function ZFYVE19 mutations are associated with congenital hepatic fibrosis, sclerosing cholangiopathy and high-GGT cholestasis.9
248145152014ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4.64
248145152014ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4.64
126187662003A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15.4
126187662003A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15.4

Citation

Dessen P

ZFYVE19 (zinc finger FYVE-type containing 19)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54800/meetings/gene-fusions-explorer/js/lib/popper.js