AZI2 (5-azacytidine induced 2)

2014-09-01  

Identity

HGNC
AZI2
LOCATION
3p24.1
LOCUSID
64343
ALIAS
AZ2,NAP1,TILP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64343
MIM: 609916
HGNC: 24002
Ensembl: ENSG00000163512

Variants:

dbSNP: 64343
ClinVar: 64343
TCGA: ENSG00000163512
COSMIC: AZI2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163512ENST00000334100Q9H6S1
ENSG00000163512ENST00000414162C9JVK8
ENSG00000163512ENST00000415852C9JGA2
ENSG00000163512ENST00000420543Q9H6S1
ENSG00000163512ENST00000429369H7C1Z1
ENSG00000163512ENST00000457172Q9H6S1
ENSG00000163512ENST00000479665Q9H6S1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
RIG-I-like receptor signaling pathwayKEGGko04622
RIG-I-like receptor signaling pathwayKEGGhsa04622

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377339212024AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer.0
380599002024NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis.0
377339212024AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer.0
380599002024NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis.0
289838432018(AZI2)3'UTR Is a New SLC6A3 Downregulator Associated with an Epistatic Protection Against Substance Use Disorders.7
289838432018(AZI2)3'UTR Is a New SLC6A3 Downregulator Associated with an Epistatic Protection Against Substance Use Disorders.7
179820772007Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA.37
179820772007Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA.37
171427682006NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.57
171427682006NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.57
145600222003Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.68
145600222003Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.68

Citation

Dessen P

AZI2 (5-azacytidine induced 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54892/img/tumors-explorer/css/template-nav.css