ABR (ABR activator of RhoGEF and GTPase)

2003-02-01  

Identity

HGNC
LOCATION
17p13.3
LOCUSID
ALIAS
MDB
FUSION GENES

Other Information

Locus ID:

NCBI: 29
MIM: 600365
HGNC: 81
Ensembl: ENSG00000159842

Variants:

dbSNP: 29
ClinVar: 29
TCGA: ENSG00000159842
COSMIC: ABR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159842ENST00000291107Q12979
ENSG00000159842ENST00000302538Q12979
ENSG00000159842ENST00000536794B7Z683
ENSG00000159842ENST00000543210Q12979
ENSG00000159842ENST00000544583Q12979
ENSG00000159842ENST00000570441I3L2P5
ENSG00000159842ENST00000570525I3L2L3
ENSG00000159842ENST00000571797I3NI05
ENSG00000159842ENST00000571945I3L1U8
ENSG00000159842ENST00000572152I3L379
ENSG00000159842ENST00000572441I3L2C0
ENSG00000159842ENST00000574139I3L4Y1
ENSG00000159842ENST00000574266I3L259
ENSG00000159842ENST00000574437A0A1C7CYZ0
ENSG00000159842ENST00000574544I3L0R7
ENSG00000159842ENST00000575770A0A0D9SGD7
ENSG00000159842ENST00000575934I3L3W0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signalling by NGFREACTOMER-HSA-166520
p75 NTR receptor-mediated signallingREACTOMER-HSA-193704
Cell death signalling via NRAGE, NRIF and NADEREACTOMER-HSA-204998
NRAGE signals death through JNKREACTOMER-HSA-193648
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (12/13) signalling eventsREACTOMER-HSA-416482

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
119213392002Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs.16
285793912017A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells.2
315163092019Genomic/proteomic analyses of dexamethasone-treated human trabecular meshwork cells reveal a role for GULP1 and ABR in phagocytosis.2

Citation

Dessen P

ABR (ABR activator of RhoGEF and GTPase)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/549/abr