ZFP57 (ZFP57 zinc finger protein)

2015-02-01  

Identity

HGNC
ZFP57
LOCATION
6p22.1
LOCUSID
346171
ALIAS
C6orf40,TNDM1,ZNF698,bA145L22,bA145L22.2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 346171
MIM: 612192
HGNC: 18791
Ensembl: ENSG00000204644

Variants:

dbSNP: 346171
ClinVar: 346171
TCGA: ENSG00000204644
COSMIC: ZFP57

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204644ENST00000376881Q9NU63
ENSG00000204644ENST00000376883Q9NU63
ENSG00000204644ENST00000488757Q9NU63
ENSG00000204644ENST00000488757A0A1U9X8V5

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
351752392022Mutational Alterations of DNA Methylation-related Genes CTCF, ZFP57, and ATF7IP Genes in Colon Cancers.0
351752392022Mutational Alterations of DNA Methylation-related Genes CTCF, ZFP57, and ATF7IP Genes in Colon Cancers.0
335003482021ZFP57 dictates allelic expression switch of target imprinted genes.8
335003482021ZFP57 dictates allelic expression switch of target imprinted genes.8
330531562020The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances.23
330531562020The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances.23
306947872019The Embryonic Stem Cell-Specific Transcription Factor ZFP57 Promotes Liver Metastasis of Colorectal Cancer.9
307872682019ZFP57 suppress proliferation of breast cancer cells through down-regulation of MEST-mediated Wnt/β-catenin signalling pathway.20
306947872019The Embryonic Stem Cell-Specific Transcription Factor ZFP57 Promotes Liver Metastasis of Colorectal Cancer.9
307872682019ZFP57 suppress proliferation of breast cancer cells through down-regulation of MEST-mediated Wnt/β-catenin signalling pathway.20
294840332018Is ZFP57 binding to H19/IGF2:IG-DMR affected in Silver-Russell syndrome?13
294840332018Is ZFP57 binding to H19/IGF2:IG-DMR affected in Silver-Russell syndrome?13
270753682016Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57.17
270753682016Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57.17
244690602015The stem cell transcription factor ZFP57 induces IGF2 expression to promote anchorage-independent growth in cancer cells.20

Citation

Dessen P

ZFP57 (ZFP57 zinc finger protein)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54980/teaching-explorer/css/template-card.css