SVIP (small VCP interacting protein)

2015-08-01  

Identity

HGNC
SVIP
LOCATION
11p14.3
LOCUSID
258010
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 258010
HGNC: 25238
Ensembl: ENSG00000198168

Variants:

dbSNP: 258010
ClinVar: 258010
TCGA: ENSG00000198168
COSMIC: SVIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198168ENST00000354193Q8NHG7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373742832023A Determination of p97/VCP (Valosin Containing Protein) and SVIP (Small VCP Interacting Protein) Expression Patterns in Human Testis.0
374081962023Differential Expression and Function of SVIP in Breast Cancer Cell Lines and In Silico Analysis of Its Expression and Prognostic Potential in Human Breast Cancer.0
373742832023A Determination of p97/VCP (Valosin Containing Protein) and SVIP (Small VCP Interacting Protein) Expression Patterns in Human Testis.0
374081962023Differential Expression and Function of SVIP in Breast Cancer Cell Lines and In Silico Analysis of Its Expression and Prognostic Potential in Human Breast Cancer.0
334792402021SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.26
334792402021SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.26
306838432019SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.17
306838432019SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.17
283014992017SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78.9
283014992017SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78.9
240558752013Structure and expression of a novel compact myelin protein - small VCP-interacting protein (SVIP).10
241002252013Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.7
240558752013Structure and expression of a novel compact myelin protein - small VCP-interacting protein (SVIP).10
241002252013Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.7
219093942011SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy.22

Citation

Dessen P

SVIP (small VCP interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55368/gene-fusions/js/web-card-_common.js