RUFY3 (RUN and FYVE domain containing 3)

2015-12-01  

Identity

HGNC
LOCATION
4q13.3
LOCUSID
ALIAS
RIPX,SINGAR1,ZFYVE30
FUSION GENES

Other Information

Locus ID:

NCBI: 22902
MIM: 611194
HGNC: 30285
Ensembl: ENSG00000018189

Variants:

dbSNP: 22902
ClinVar: 22902
TCGA: ENSG00000018189
COSMIC: RUFY3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000018189ENST00000226328Q7L099
ENSG00000018189ENST00000226328A0A024RDD7
ENSG00000018189ENST00000381006Q7L099
ENSG00000018189ENST00000417478Q7L099
ENSG00000018189ENST00000502653Q7L099
ENSG00000018189ENST00000503876D6REM9
ENSG00000018189ENST00000504805H0Y8I0
ENSG00000018189ENST00000512103H0Y8G6
ENSG00000018189ENST00000513597D6RCQ1
ENSG00000018189ENST00000514898D6RH24

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
389150532024circSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA.0
389150532024circSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA.0
377976942023HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover.0
377976942023HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover.0
350185432022Low RUFY3 expression level is associated with lymph node metastasis in older women with invasive breast cancer.3
350185432022Low RUFY3 expression level is associated with lymph node metastasis in older women with invasive breast cancer.3
345100312021RUFY3 promotes the progression of hepatocellular carcinoma through activating NF-κB-mediated epithelial-mesenchymal transition.4
345100312021RUFY3 promotes the progression of hepatocellular carcinoma through activating NF-κB-mediated epithelial-mesenchymal transition.4
327442432020Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases.3
327442432020Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases.3
315478402019HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.33
315478402019HOXD9 promotes the growth, invasion and metastasis of gastric cancer cells by transcriptional activation of RUFY3.33
286233232017RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.19
286233232017RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancer.19
257663212015PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion.32

Citation

Dessen P

RUFY3 (RUN and FYVE domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-12-01

Online version: http://atlasgeneticsoncology.org/gene/55544/favicon/css/lib/dataTables.bootstrap.min.css