COA1 (cytochrome c oxidase assembly factor 1)

2016-05-01  

Identity

HGNC
COA1
LOCATION
7p13
LOCUSID
55744
ALIAS
C7orf44,MITRAC15
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55744
MIM: 614769
HGNC: 21868
Ensembl: ENSG00000106603

Variants:

dbSNP: 55744
ClinVar: 55744
TCGA: ENSG00000106603
COSMIC: COA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106603ENST00000223336Q9GZY4
ENSG00000106603ENST00000223336A0A024RA60
ENSG00000106603ENST00000310564Q9GZY4
ENSG00000106603ENST00000310564A0A024RA60
ENSG00000106603ENST00000395879Q9GZY4
ENSG00000106603ENST00000395879A0A024RA60
ENSG00000106603ENST00000415076Q9GZY4
ENSG00000106603ENST00000415076A0A024RA60
ENSG00000106603ENST00000415798C9JA07
ENSG00000106603ENST00000418140F2Z2J3
ENSG00000106603ENST00000420441F2Z2D1
ENSG00000106603ENST00000431651C9J6J1
ENSG00000106603ENST00000438444Q9GZY4
ENSG00000106603ENST00000438444A0A024RA60
ENSG00000106603ENST00000446330Q9GZY4
ENSG00000106603ENST00000446330A0A024RA60
ENSG00000106603ENST00000446564Q9GZY4
ENSG00000106603ENST00000446564A0A024RA60
ENSG00000106603ENST00000448704F2Z2D1
ENSG00000106603ENST00000451651F8WBS2
ENSG00000106603ENST00000457939F2Z2J3

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
340810572021Association of COA1 with Patellar Tendonitis: A Genome-wide Association Analysis.1
340810572021Association of COA1 with Patellar Tendonitis: A Genome-wide Association Analysis.1
317214202020MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome-nascent chain complex.19
317214202020MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome-nascent chain complex.19
266559972016Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6.15
266559972016Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6.15
223568262012Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.48
223568262012Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.48
223568262012Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.48
223568262012Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.48

Citation

Dessen P

COA1 (cytochrome c oxidase assembly factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55784/img/js/template.js