IFNE (interferon epsilon)

2016-10-01 Affiliation

Identity

HGNC

IFNE

LOCATION

9p21.3

LOCUSID

338376

ALIAS

IFN-E,IFNE1,IFNT1,INFE1,PRO655

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 338376
MIM: 615223
HGNC: 18163
Ensembl: ENSG00000184995

Variants:

dbSNP: 338376
ClinVar: 338376
TCGA: ENSG00000184995
COSMIC: IFNE

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000184995	ENST00000448696	Q86WN2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Cytokine-cytokine receptor interaction	KEGG	ko04060
Jak-STAT signaling pathway	KEGG	ko04630
Cytokine-cytokine receptor interaction	KEGG	hsa04060
Jak-STAT signaling pathway	KEGG	hsa04630
RIG-I-like receptor signaling pathway	KEGG	ko04622
RIG-I-like receptor signaling pathway	KEGG	hsa04622

References

Pubmed ID	Year	Title	Citations
17878351	2007	IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells.	20
20574843	2010	Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.	18
20601674	2010	Bivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study.	10
20588308	2010	Dengue hemorrhagic fever is associated with polymorphisms in JAK1.	9
23851686	2013	Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.	4
18842358	2008	[Anti-HIV effects of IFN-tau in human macrophages: role of cellular antiviral factors and interleukin-6].	2
15233997	2004	Characterization of the type I interferon locus and identification of novel genes.	0
18362232	2008	Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.	0
23802172	2013	Association study between nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε and susceptibility to vitiligo in Korean population.	0
24055696	2014	T Allele of nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε is a risk factor for the development of intracerebral hemorrhage.	0

Citation

Dessen P

IFNE (interferon epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55988/ifne