CDC123 (cell division cycle 123)

2016-10-01  

Identity

HGNC
CDC123
LOCATION
10p14
LOCUSID
8872
ALIAS
C10orf7,D123
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8872
MIM: 617708
HGNC: 16827
Ensembl: ENSG00000151465

Variants:

dbSNP: 8872
ClinVar: 8872
TCGA: ENSG00000151465
COSMIC: CDC123

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151465ENST00000281141O75794
ENSG00000151465ENST00000378900X6RA30
ENSG00000151465ENST00000429258X6RKY7
ENSG00000151465ENST00000440613H7BZW7
ENSG00000151465ENST00000442050X6RF82

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382374002024CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.0
382374002024CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.0
373142162023USP9X deubiquitinates and stabilizes CDC123 to promote breast carcinogenesis through regulating cell cycle.0
375070292023Binding of human Cdc123 to eIF2γ.0
373142162023USP9X deubiquitinates and stabilizes CDC123 to promote breast carcinogenesis through regulating cell cycle.0
375070292023Binding of human Cdc123 to eIF2γ.0
280798682017CDC123/CAMK1D gene rs12779790 polymorphism and rs10811661 polymorphism upstream of the CDKN2A/2B gene in women with gestational diabetes.8
280798682017CDC123/CAMK1D gene rs12779790 polymorphism and rs10811661 polymorphism upstream of the CDKN2A/2B gene in women with gestational diabetes.8
259766112015The eukaryotic translation initiation regulator CDC123 defines a divergent clade of ATP-grasp enzymes with a predicted role in novel protein modifications.9
259766112015The eukaryotic translation initiation regulator CDC123 defines a divergent clade of ATP-grasp enzymes with a predicted role in novel protein modifications.9
229234682012Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.54
229234682012Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.54
208898532011Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.75
219098392011Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population.17
208898532011Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.75

Citation

Dessen P

CDC123 (cell division cycle 123)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56084/gene-fusions/gene-explorer/js/lib/popper.js