YME1L1 (YME1 like 1 ATPase)

2016-10-01  

Identity

HGNC
YME1L1
LOCATION
10p12.1
LOCUSID
10730
ALIAS
FTSH,MEG4,OPA11,PAMP,YME1L
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10730
MIM: 607472
HGNC: 12843
Ensembl: ENSG00000136758

Variants:

dbSNP: 10730
ClinVar: 10730
TCGA: ENSG00000136758
COSMIC: YME1L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136758ENST00000326799Q96TA2
ENSG00000136758ENST00000375972Q96I63
ENSG00000136758ENST00000376016Q96TA2
ENSG00000136758ENST00000396296Q5T8D2
ENSG00000136758ENST00000427324Q5T8D1
ENSG00000136758ENST00000477432Q6PJ89
ENSG00000136758ENST00000491542R4GNA5
ENSG00000136758ENST00000613434Q96TA2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387691242024Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo.1
387691242024Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo.1
370634262023The mitochondrial protein YME1 Like 1 is important for non-small cell lung cancer cell growth.6
370634262023The mitochondrial protein YME1 Like 1 is important for non-small cell lung cancer cell growth.6
320870622020Regulation of mitochondrial plasticity by the i-AAA protease YME1L.21
331557942020Examination of the Role of Mg(2+) in the Mechanism of Nucleotide Binding to the Monomeric YME1L AAA+ Domain.1
320870622020Regulation of mitochondrial plasticity by the i-AAA protease YME1L.21
331557942020Examination of the Role of Mg(2+) in the Mechanism of Nucleotide Binding to the Monomeric YME1L AAA+ Domain.1
305984792019ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.22
316951972019Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.71
305984792019ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.22
316951972019Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.71
283561572017Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma.31
283561572017Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma.31
269235992016Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress.88

Citation

Dessen P

YME1L1 (YME1 like 1 ATPase)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56105/js/lib/zoomerang.js