BTN2A2 (butyrophilin subfamily 2 member A2)

2016-10-01  

Identity

HGNC
BTN2A2
LOCATION
6p22.2
LOCUSID
10385
ALIAS
BT2.2,BTF2,BTN2.2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10385
MIM: 613591
HGNC: 1137
Ensembl: ENSG00000124508

Variants:

dbSNP: 10385
ClinVar: 10385
TCGA: ENSG00000124508
COSMIC: BTN2A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124508ENST00000352867Q8WVV5
ENSG00000124508ENST00000356709Q8WVV5
ENSG00000124508ENST00000356709A0A024R038
ENSG00000124508ENST00000416795Q8WVV5
ENSG00000124508ENST00000416795A0A024R038
ENSG00000124508ENST00000432533Q8WVV5
ENSG00000124508ENST00000469230Q8WVV5
ENSG00000124508ENST00000471116F8WC65
ENSG00000124508ENST00000472507C9JWH2
ENSG00000124508ENST00000482536Q8WVV5
ENSG00000124508ENST00000482842C9J8R3
ENSG00000124508ENST00000483410C9J8J5
ENSG00000124508ENST00000490025C9IZY2
ENSG00000124508ENST00000493275C9IY66
ENSG00000124508ENST00000494184C9JAJ6
ENSG00000124508ENST00000495632H7C4E8

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Butyrophilin (BTN) family interactionsREACTOMER-HSA-8851680

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376343142023Frameshift mutations of immunomodulatory BTN2A1, BTN2A2, and BTNL3 genes in colon cancers.0
376343142023Frameshift mutations of immunomodulatory BTN2A1, BTN2A2, and BTNL3 genes in colon cancers.0
268094442016Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.33
268094442016Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.33

Citation

Dessen P

BTN2A2 (butyrophilin subfamily 2 member A2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56137/deep-insight-explorer/deep-insight-explorer/js/web-card-_common.js