CKM (creatine kinase, M-type)

2016-10-01  

Identity

HGNC
CKM
LOCATION
19q13.32
LOCUSID
1158
ALIAS
CKMM,CPK-M,M-CK
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1158
MIM: 123310
HGNC: 1994
Ensembl: ENSG00000104879

Variants:

dbSNP: 1158
ClinVar: 1158
TCGA: ENSG00000104879
COSMIC: CKM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104879ENST00000221476P06732

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Arginine and proline metabolismKEGGko00330
Arginine and proline metabolismKEGGhsa00330
Metabolic pathwaysKEGGhsa01100
Creatine pathwayKEGGhsa_M00047
Creatine pathwayKEGGM00047
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Creatine metabolismREACTOMER-HSA-71288
Metabolism of polyaminesREACTOMER-HSA-351202

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
325572532021Ancestral contribution of the muscle-specific creatine kinase (CKM) polymorphism rs4884 in the knee osteoarthritis risk: a preliminary study.1
335549562021Acetylation of muscle creatine kinase negatively impacts high-energy phosphotransfer in heart failure.8
346808942021CKM Gene rs8111989 Polymorphism and Power Athlete Status.4
349411182021The role of serum creatine kinase levels in anterior cervical spinal surgery: Change trends and risk factors.1
325572532021Ancestral contribution of the muscle-specific creatine kinase (CKM) polymorphism rs4884 in the knee osteoarthritis risk: a preliminary study.1
335549562021Acetylation of muscle creatine kinase negatively impacts high-energy phosphotransfer in heart failure.8
346808942021CKM Gene rs8111989 Polymorphism and Power Athlete Status.4
349411182021The role of serum creatine kinase levels in anterior cervical spinal surgery: Change trends and risk factors.1
316788282020Using SERS-based microfluidic paper-based device (μPAD) for calibration-free quantitative measurement of AMI cardiac biomarkers.13
319822712020Serological risk factors for concomitant interstitial lung disease in patients with idiopathic inflammatory myopathy.4
330295252020Population-Wide Duchenne Muscular Dystrophy Carrier Detection by CK and Molecular Testing.6
316788282020Using SERS-based microfluidic paper-based device (μPAD) for calibration-free quantitative measurement of AMI cardiac biomarkers.13
319822712020Serological risk factors for concomitant interstitial lung disease in patients with idiopathic inflammatory myopathy.4
330295252020Population-Wide Duchenne Muscular Dystrophy Carrier Detection by CK and Molecular Testing.6
307102352019Do ACE and CKMM gene variations have potent effects on physical performance in inactive male adolescents?1

Citation

Dessen P

CKM (creatine kinase, M-type)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56513/tumors-explorer/gene-fusions-explorer/js/web-card-gene.js