CD207 (CD207 molecule)

CD207 (CD207 molecule)

2016-10-01 Affiliation

Identity

HGNC

LOCATION

2p13.3

LOCUSID

ALIAS

CLEC4K

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 50489
MIM: 604862
HGNC: 17935
Ensembl: ENSG00000116031

Variants:

dbSNP: 50489
ClinVar: 50489
TCGA: ENSG00000116031
COSMIC: CD207

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000116031	ENST00000410009	Q9UJ71

Expression (GTEx)

0

5

10

15

20

25

30

35

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
Class I MHC mediated antigen processing & presentation	REACTOME	R-HSA-983169
Antigen processing-Cross presentation	REACTOME	R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes)	REACTOME	R-HSA-1236978

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34935212	2022	Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions.	1
34935212	2022	Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions.	1
33989634	2021	The molecular basis for the pH-dependent calcium affinity of the pattern recognition receptor langerin.	4
33989634	2021	The molecular basis for the pH-dependent calcium affinity of the pattern recognition receptor langerin.	4
31141812	2020	A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus.	5
31607745	2020	Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells.	7
31141812	2020	A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus.	5
31607745	2020	Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells.	7
29631057	2018	High affinity sugar ligands of C-type lectin receptor langerin.	10
29631057	2018	High affinity sugar ligands of C-type lectin receptor langerin.	10
26456691	2017	Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells.	22
27903635	2017	Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent.	16
28198086	2017	Calcium-Independent Activation of an Allosteric Network in Langerin by Heparin Oligosaccharides.	7
28847997	2017	CD207(+)CD1a(+) cells circulate in pediatric patients with active Langerhans cell histiocytosis.	16
26456691	2017	Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells.	22

Citation

Dessen P

CD207 (CD207 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56545/img/js/lib/jquery-3.5.1.min.js