UBAP2 (ubiquitin associated protein 2)

2017-08-01  

Identity

HGNC
UBAP2
LOCATION
9p13.3
LOCUSID
55833
ALIAS
UBAP-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55833
HGNC: 14185
Ensembl: ENSG00000137073

Variants:

dbSNP: 55833
ClinVar: 55833
TCGA: ENSG00000137073
COSMIC: UBAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137073ENST00000360802Q5T6F2
ENSG00000137073ENST00000379238Q5T6F2
ENSG00000137073ENST00000379239Q5T6F2
ENSG00000137073ENST00000412543A2A305
ENSG00000137073ENST00000421278Q5JV08
ENSG00000137073ENST00000488443H0YDN2
ENSG00000137073ENST00000629575A0A0D9SFI5

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379620452024Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating the miR-143/TFAP2B Axis in Prostate Cancer.1
379620452024Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating the miR-143/TFAP2B Axis in Prostate Cancer.1
378480332023PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly.4
378480332023PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly.4
356335972022UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.8
356335972022UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.8
335438302021Circ-UBAP2 functions as sponges of miR-1205 and miR-382 to promote glioma progression by modulating STC1 expression.11
343460322021Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells.8
335438302021Circ-UBAP2 functions as sponges of miR-1205 and miR-382 to promote glioma progression by modulating STC1 expression.11
343460322021Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells.8
326900862020circRNA-UBAP2 promotes the proliferation and inhibits apoptosis of ovarian cancer though miR-382-5p/PRPF8 axis.26
326924452020Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer.6
326900862020circRNA-UBAP2 promotes the proliferation and inhibits apoptosis of ovarian cancer though miR-382-5p/PRPF8 axis.26
326924452020Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer.6
303147062018Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.47

Citation

Dessen P

UBAP2 (ubiquitin associated protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56932/gene-explorer/teaching-explorer/css/lib/dataTables.bootstrap.min.css