ONECUT3 (one cut homeobox 3)

2017-10-01  

Identity

HGNC
ONECUT3
LOCATION
19p13.3
LOCUSID
390874
ALIAS
OC3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 390874
MIM: 611294
HGNC: 13399
Ensembl: ENSG00000205922

Variants:

dbSNP: 390874
ClinVar: 390874
TCGA: ENSG00000205922
COSMIC: ONECUT3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205922ENST00000382349O60422

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Regulation of beta-cell developmentREACTOMER-HSA-186712
Regulation of gene expression in early pancreatic precursor cellsREACTOMER-HSA-210747
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cellsREACTOMER-HSA-210744

References

Pubmed IDYearTitleCitations
383864142024Ectopic expression of the transcription factor ONECUT3 drives a complex karyotype in myelodysplastic syndromes.0
383864142024Ectopic expression of the transcription factor ONECUT3 drives a complex karyotype in myelodysplastic syndromes.0
378755892023Identification of ONECUT3 as a stemness-related transcription factor regulating NK cell-mediated immune evasion in pancreatic cancer.0
378755892023Identification of ONECUT3 as a stemness-related transcription factor regulating NK cell-mediated immune evasion in pancreatic cancer.0
310495882019ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.27
310495882019ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.27
284646012017Discrimination of CD44 and Oct3/4 Expression in Pancreatic Adenocarcinoma from Benign Pancreatic Ducts in Small Biopsy Specimens.1
284646012017Discrimination of CD44 and Oct3/4 Expression in Pancreatic Adenocarcinoma from Benign Pancreatic Ducts in Small Biopsy Specimens.1

Citation

Dessen P

ONECUT3 (one cut homeobox 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57117/teaching-explorer/js/favicon/css/lib/bootstrap.min.css