TRIM47 (tripartite motif containing 47)

2017-10-01  

Identity

HGNC
TRIM47
LOCATION
17q25.1
LOCUSID
91107
ALIAS
GOA,RNF100
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 91107
MIM: 611041
HGNC: 19020
Ensembl: ENSG00000132481

Variants:

dbSNP: 91107
ClinVar: 91107
TCGA: ENSG00000132481
COSMIC: TRIM47

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132481ENST00000254816Q96LD4
ENSG00000132481ENST00000585333K7EQ30
ENSG00000132481ENST00000586495K7EJ63
ENSG00000132481ENST00000587339A0A0M3HER3

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386142262024TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.0
386142262024TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.0
362030702022TRIM47 promotes glioma angiogenesis by suppressing Smad4.0
362886332022TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.1
362030702022TRIM47 promotes glioma angiogenesis by suppressing Smad4.0
362886332022TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.1
333508492021Trim47 overexpression correlates with poor prognosis in gastric cancer.8
335297532021TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer.16
338338242021Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter.4
344336662021TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer.17
333508492021Trim47 overexpression correlates with poor prognosis in gastric cancer.8
335297532021TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer.16
338338242021Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter.4
344336662021TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer.17
326037622020Knockdown of TRIM47 inhibits glioma cell proliferation, migration and invasion through the inactivation of Wnt/β-catenin pathway.10

Citation

Dessen P

TRIM47 (tripartite motif containing 47)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57159/favicon/css/lib/css/lib/bootstrap.min.css