CA10 (carbonic anhydrase 10)

2017-10-01  

Identity

HGNC
CA10
LOCATION
17q21.33
LOCUSID
56934
ALIAS
CA-RPX,CARPX,HUCEP-15
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56934
MIM: 604642
HGNC: 1369
Ensembl: ENSG00000154975

Variants:

dbSNP: 56934
ClinVar: 56934
TCGA: ENSG00000154975
COSMIC: CA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154975ENST00000285273Q9NS85
ENSG00000154975ENST00000285273A0A384MTY8
ENSG00000154975ENST00000442502Q9NS85
ENSG00000154975ENST00000442502A0A384MTY8
ENSG00000154975ENST00000451037Q9NS85
ENSG00000154975ENST00000451037A0A384MTY8
ENSG00000154975ENST00000570565Q9NS85
ENSG00000154975ENST00000571371I3NI54
ENSG00000154975ENST00000575097I3L0J7
ENSG00000154975ENST00000575181I3L375

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD24407380
PA449686fluticasone propionateChemicalClinicalAnnotationassociatedPD24407380
PA450546montelukastChemicalClinicalAnnotationassociatedPD24407380

References

Pubmed IDYearTitleCitations
349805442022Carbonic anhydrase 10 functions as a tumor suppressor in renal cell carcinoma and its methylation is a risk factor for survival outcome.1
349805442022Carbonic anhydrase 10 functions as a tumor suppressor in renal cell carcinoma and its methylation is a risk factor for survival outcome.1
326183672020Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.3
327365392020Methylation of WT1, CA10 in peripheral blood leukocyte is associated with breast cancer risk: a case-control study.3
326183672020Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.3
327365392020Methylation of WT1, CA10 in peripheral blood leukocyte is associated with breast cancer risk: a case-control study.3
306360762019CA10 and CA11 negatively regulate neuronal activity-dependent growth of gliomas.6
306360762019CA10 and CA11 negatively regulate neuronal activity-dependent growth of gliomas.6
292916172018Methylation Status of Transcriptional Modulatory Genes Associated with Colorectal Cancer in Northeast China.6
292916172018Methylation Status of Transcriptional Modulatory Genes Associated with Colorectal Cancer in Northeast China.6
281541402017Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.59
285372442017[Transcription factors NF-kB, HIF-1, HIF-2, growth factor VEGF, VEGFR2 and carboanhydrase IX mRNA and protein level in the development of kidney cancer metastasis].10
281541402017Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.59
285372442017[Transcription factors NF-kB, HIF-1, HIF-2, growth factor VEGF, VEGFR2 and carboanhydrase IX mRNA and protein level in the development of kidney cancer metastasis].10
258800852015A genome-wide association study of copy-number variation identifies putative loci associated with osteoarthritis in Koreans.4

Citation

Dessen P

CA10 (carbonic anhydrase 10)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57185/deep-insight-explorer/gene-explorer/favicon/apple-touch-icon.png