CRTAC1 (cartilage acidic protein 1)

2017-10-01  

Identity

HGNC
CRTAC1
LOCATION
10q24.2
LOCUSID
55118
ALIAS
ASPIC,ASPIC1,CEP-68,CEP68,LOTUS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55118
MIM: 606276
HGNC: 14882
Ensembl: ENSG00000095713

Variants:

dbSNP: 55118
ClinVar: 55118
TCGA: ENSG00000095713
COSMIC: CRTAC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000095713ENST00000309155A0A0C4DFP6
ENSG00000095713ENST00000370591Q9NQ79
ENSG00000095713ENST00000370597Q9NQ79
ENSG00000095713ENST00000413387Q5T4F6
ENSG00000095713ENST00000436034H0Y6C6

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359249622023Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression.11
362393772023Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource.8
364106352023The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis.6
370395592023Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening.0
359249622023Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression.11
362393772023Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource.8
364106352023The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis.6
370395592023Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening.0
356067862022Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers.7
356067862022Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers.7
339828932021The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland.20
342699612021Deciphering the role of cartilage protein 1 in human dermal fibroblasts: a transcriptomic approach.1
348189942021CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway.12
339828932021The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland.20
342699612021Deciphering the role of cartilage protein 1 in human dermal fibroblasts: a transcriptomic approach.1

Citation

Dessen P

CRTAC1 (cartilage acidic protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57186/teaching-explorer/favicon/css/lib/dataTables.bootstrap.min.css