ZNF322 (zinc finger protein 322)

2017-10-01  

Identity

HGNC
ZNF322
LOCATION
6p22.2
LOCUSID
79692
ALIAS
HCG12,ZNF322A,ZNF388,ZNF489
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79692
MIM: 610847
HGNC: 23640
Ensembl: ENSG00000181315

Variants:

dbSNP: 79692
ClinVar: 79692
TCGA: ENSG00000181315
COSMIC: ZNF322

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181315ENST00000415922Q6U7Q0
ENSG00000181315ENST00000415922A0A024QZZ4
ENSG00000181315ENST00000456172Q6U7Q0
ENSG00000181315ENST00000456172A0A024QZZ4
ENSG00000181315ENST00000471278Q6U7Q0
ENSG00000181315ENST00000471278A0A024QZZ4
ENSG00000181315ENST00000480036C9JP13
ENSG00000181315ENST00000607204Q6U7Q0
ENSG00000181315ENST00000607204A0A024QZZ4
ENSG00000181315ENST00000622479Q6U7Q0
ENSG00000181315ENST00000622479A0A024QZZ4

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376472092024Downregulation of microRNA-326 enhances ZNF322A expression, transcriptional activity and tumorigenic effects in lung cancer.0
376472092024Downregulation of microRNA-326 enhances ZNF322A expression, transcriptional activity and tumorigenic effects in lung cancer.0
325761962020ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer.6
329293302020Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression.16
325761962020ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer.6
329293302020Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression.16
302580972019Oncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression.10
313996472019AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression.11
302580972019Oncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression.10
313996472019AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression.11
288804892018miRNA-4317 suppresses human gastric cancer cell proliferation by targeting ZNF322.25
288804892018miRNA-4317 suppresses human gastric cancer cell proliferation by targeting ZNF322.25
285815252017CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression.8
285815252017CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression.8
262793042016Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.25

Citation

Dessen P

ZNF322 (zinc finger protein 322)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57218/js/js/lib/bootstrap.min.js