KLF7 (Kruppel like factor 7)

2018-02-01  

Identity

HGNC
KLF7
LOCATION
2q33.3
LOCUSID
8609
ALIAS
UKLF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8609
MIM: 604865
HGNC: 6350
Ensembl: ENSG00000118263

Variants:

dbSNP: 8609
ClinVar: 8609
TCGA: ENSG00000118263
COSMIC: KLF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118263ENST00000309446O75840
ENSG00000118263ENST00000309446A0A024R3X8
ENSG00000118263ENST00000412414O75840
ENSG00000118263ENST00000421199O75840
ENSG00000118263ENST00000423015O75840
ENSG00000118263ENST00000426163E7EQY2
ENSG00000118263ENST00000435602C9JX20
ENSG00000118263ENST00000451244E9PHC9
ENSG00000118263ENST00000457962E7EUU0
ENSG00000118263ENST00000458272O75840

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384439912024KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma.1
387689272024UKLF/PCBP2 axis governs the colorectal cancer development by transcriptionally activating SLC39A4.0
384439912024KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma.1
387689272024UKLF/PCBP2 axis governs the colorectal cancer development by transcriptionally activating SLC39A4.0
362427282023LncRNA NUTM2A-AS1 aggravates the progression of hepatocellular carcinoma by activating the miR-186-5p/KLF7-mediated Wnt/beta-catenin pathway.3
367175282023Circular hsa_circ_0020377 regulates KLF7 by targeting miR-194-5p to facilitate tumor cell malignant behaviors and glycolysis in oral squamous cell carcinoma progression.1
372271542023Molecular function of Krüppel-like factor 7 in biology.1
375542782023HMGB1-mediated elevation of KLF7 facilitates hepatocellular carcinoma progression and metastasis through upregulating TLR4 and PTK2.0
362427282023LncRNA NUTM2A-AS1 aggravates the progression of hepatocellular carcinoma by activating the miR-186-5p/KLF7-mediated Wnt/beta-catenin pathway.3
367175282023Circular hsa_circ_0020377 regulates KLF7 by targeting miR-194-5p to facilitate tumor cell malignant behaviors and glycolysis in oral squamous cell carcinoma progression.1
372271542023Molecular function of Krüppel-like factor 7 in biology.1
375542782023HMGB1-mediated elevation of KLF7 facilitates hepatocellular carcinoma progression and metastasis through upregulating TLR4 and PTK2.0
333931692022KLF7 is associated with poor prognosis and regulates migration and adhesion in tongue cancer.6
347838942022LncRNA SNHG14 accelerates breast cancer progression through sponging miR-543 and regulating KLF7 expression.3
353287992022Krüppel-like Transcription Factor 7 Is a Causal Gene in Autism Development.2

Citation

Dessen P

KLF7 (Kruppel like factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57351/js/lib/js/lib/css/lib/dataTables.bootstrap.min.css