SEC61A2 (SEC61 translocon subunit alpha 2)

2018-07-01  

Identity

HGNC
LOCATION
10p14
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 55176
MIM: 618271
HGNC: 17702
Ensembl: ENSG00000065665

Variants:

dbSNP: 55176
ClinVar: 55176
TCGA: ENSG00000065665
COSMIC: SEC61A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000065665ENST00000298428Q9H9S3
ENSG00000065665ENST00000304267Q9H9S3
ENSG00000065665ENST00000379017A6NIF9
ENSG00000065665ENST00000379020F8W776
ENSG00000065665ENST00000379033Q9H9S3
ENSG00000065665ENST00000379051A6NK38
ENSG00000065665ENST00000418772H7C069
ENSG00000065665ENST00000419021H7C1S8
ENSG00000065665ENST00000441368C9JJV4
ENSG00000065665ENST00000457034H7C1Q9
ENSG00000065665ENST00000472221F2Z2C7
ENSG00000065665ENST00000475268Q8TC24

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Protein exportKEGGko03060
Vibrio cholerae infectionKEGGko05110
Protein exportKEGGhsa03060
Vibrio cholerae infectionKEGGhsa05110
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Sec61 complexKEGGhsa_M00401
Sec61 complexKEGGM00401
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Unfolded Protein Response (UPR)REACTOMER-HSA-381119
IRE1alpha activates chaperonesREACTOMER-HSA-381070
XBP1(S) activates chaperone genesREACTOMER-HSA-381038
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing-Cross presentationREACTOMER-HSA-1236975
ER-Phagosome pathwayREACTOMER-HSA-1236974
Gene ExpressionREACTOMER-HSA-74160

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69

Citation

Dessen P

SEC61A2 (SEC61 translocon subunit alpha 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57408/sec61a2