DEPDC7 (DEP domain containing 7)

2018-07-01  

Identity

HGNC
DEPDC7
LOCATION
11p13
LOCUSID
91614
ALIAS
TR2,dJ85M6.4

Other Information

Locus ID:

NCBI: 91614
MIM: 612294
HGNC: 29899
Ensembl: ENSG00000121690

Variants:

dbSNP: 91614
ClinVar: 91614
TCGA: ENSG00000121690
COSMIC: DEPDC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121690ENST00000241051Q96QD5
ENSG00000121690ENST00000311388Q96QD5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

References

Pubmed IDYearTitleCitations
270162542017Construction and Identification of the RNAi Recombinant Lentiviral Vector Targeting Human DEPDC7 Gene.5
270162542017Construction and Identification of the RNAi Recombinant Lentiviral Vector Targeting Human DEPDC7 Gene.5
259521352015Further evidence of DEPDC7 DNA hypomethylation in depression: A study in adult twins.6
259521352015Further evidence of DEPDC7 DNA hypomethylation in depression: A study in adult twins.6
255419732014The Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing protein DEPDC7 binds to CARMA2 and CARMA3 proteins, and regulates NF-κB activation.17
255419732014The Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing protein DEPDC7 binds to CARMA2 and CARMA3 proteins, and regulates NF-κB activation.17

Citation

Dessen P

DEPDC7 (DEP domain containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57412/js/favicon/favicon/favicon-32x32.png