BRD9 (bromodomain containing 9)

2019-04-01  

Identity

HGNC
BRD9
LOCATION
5p15.33
LOCUSID
65980
ALIAS
LAVS3040,PRO9856
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65980
MIM: 618465
HGNC: 25818
Ensembl: ENSG00000028310

Variants:

dbSNP: 65980
ClinVar: 65980
TCGA: ENSG00000028310
COSMIC: BRD9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000028310ENST00000466684F2Z2E8
ENSG00000028310ENST00000467963Q9H8M2
ENSG00000028310ENST00000483173Q9H8M2
ENSG00000028310ENST00000487688F2Z2E8
ENSG00000028310ENST00000489093C9JBY0
ENSG00000028310ENST00000489816F2Z2E8
ENSG00000028310ENST00000490814F2Z2E8
ENSG00000028310ENST00000495265F2Z2E8
ENSG00000028310ENST00000518250H0YBX9
ENSG00000028310ENST00000518251H0YAW8
ENSG00000028310ENST00000519112H0YBF1
ENSG00000028310ENST00000523139H0YBR9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377390892024BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.3
381267672024The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9.1
382559822024Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.1
383036082024Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours.1
377390892024BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.3
381267672024The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9.1
382559822024Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.1
383036082024Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours.1
357789642023BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma.8
364845042023Characterization of the Functional Interplay between the BRD7 and BRD9 Homologues in mSWI/SNF Complexes.0
367801892023BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma.7
378704682023BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells.3
357789642023BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma.8
364845042023Characterization of the Functional Interplay between the BRD7 and BRD9 Homologues in mSWI/SNF Complexes.0
367801892023BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma.7

Citation

Dessen P

BRD9 (bromodomain containing 9)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57877/gene-fusions-explorer/js/template.js