HNRNPLL (heterogeneous nuclear ribonucleoprotein L like)

2019-04-01  

Identity

HGNC
HNRNPLL
LOCATION
2p22.1
LOCUSID
92906
ALIAS
HNRPLL,SRRF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92906
MIM: 611208
HGNC: 25127
Ensembl: ENSG00000143889

Variants:

dbSNP: 92906
ClinVar: 92906
TCGA: ENSG00000143889
COSMIC: HNRNPLL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143889ENST00000272249H7BXH8
ENSG00000143889ENST00000358367C9IYN3
ENSG00000143889ENST00000378915B7WPG3
ENSG00000143889ENST00000409328Q8WVV9
ENSG00000143889ENST00000409636Q8WVV9
ENSG00000143889ENST00000410076Q8WVV9
ENSG00000143889ENST00000425682C9JJZ7
ENSG00000143889ENST00000441689H7C464
ENSG00000143889ENST00000449105Q8WVV9
ENSG00000143889ENST00000449105A0A0S2Z6K1
ENSG00000143889ENST00000608859D6W592

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
186698612008Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.84
187192442008A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4.58
205051492010Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from heterogeneous nuclear ribonucleoprotein L-like mutation.10
297693102018Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation.7
152562612004Alternatively spliced isoforms of a novel stromal RNA regulating factor.3
296101512018Multilevel Differential Control of Hormone Gene Expression Programs by hnRNP L and LL in Pituitary Cells.2

Citation

Dessen P

HNRNPLL (heterogeneous nuclear ribonucleoprotein L like)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57936/hnrnpll