LY6G6D (lymphocyte antigen 6 family member G6D)

2019-04-01  

Identity

HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
C6orf23,G6D,LY6-D,MEGT1,NG25

Other Information

Locus ID:

NCBI: 58530
MIM: 606038
HGNC: 13935
Ensembl: ENSG00000244355

Variants:

dbSNP: 58530
ClinVar: 58530
TCGA: ENSG00000244355
COSMIC: LY6G6D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000244355ENST00000375824F6XWZ1
ENSG00000244355ENST00000375824Q8NDY2
ENSG00000244355ENST00000375825O95868
ENSG00000244355ENST00000375825A0A1L6Z9X4

Expression (GTEx)

0
1
2
3
4
5
6
7

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
361598512022LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.3
361598512022LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.3
306700492019JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer.20
306700492019JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer.20
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35
198070192009[Detection of LY6G6D gene exon-intron structure,].0
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35
198070192009[Detection of LY6G6D gene exon-intron structure,].0

Citation

Dessen P

LY6G6D (lymphocyte antigen 6 family member G6D)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57964/css/js/template.js