CNKSR3 (CNKSR family member 3)

2019-08-01  

Identity

HGNC
LOCATION
6q25.2
LOCUSID
ALIAS
CNK3,CNK3/IPCEF1,MAGI1

Other Information

Locus ID:

NCBI: 154043
MIM: 617476
HGNC: 23034
Ensembl: ENSG00000153721

Variants:

dbSNP: 154043
ClinVar: 154043
TCGA: ENSG00000153721
COSMIC: CNKSR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153721ENST00000424998Q5T4Y8
ENSG00000153721ENST00000607772Q6P9H4

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
195673702009Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.18
220855422012CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.12
228511762012Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.9
233575032013Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival.9
224571462012Differential gene expression profile in PBMCs from subjects with AERD and ATA: a gene marker for AERD.6
300196502018Significance of miR-15a-5p and CNKSR3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer.2
284011682017The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population.1

Citation

Dessen P

CNKSR3 (CNKSR family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58090/cnksr3