ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

2021-06-01  

Identity

HGNC
ANKZF1
LOCATION
2q35
LOCUSID
55139
ALIAS
Vms1,ZNF744

Other Information

Locus ID:

NCBI: 55139
MIM: 617541
HGNC: 25527
Ensembl: ENSG00000163516

Variants:

dbSNP: 55139
ClinVar: 55139
TCGA: ENSG00000163516
COSMIC: ANKZF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163516ENST00000323348Q9H8Y5
ENSG00000163516ENST00000323348A0A024R464
ENSG00000163516ENST00000409849B8ZZS4
ENSG00000163516ENST00000410034Q9H8Y5
ENSG00000163516ENST00000410034A0A024R464
ENSG00000163516ENST00000416565C9J5H7
ENSG00000163516ENST00000435521F8WD44
ENSG00000163516ENST00000436226C9JQZ3
ENSG00000163516ENST00000447157C9K022
ENSG00000163516ENST00000453432C9JS61

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386665412024Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.0
386665412024Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.0
312579222019High ANKZF1 expression is associated with poor overall survival and recurrence-free survival in colon cancer.11
312579222019High ANKZF1 expression is associated with poor overall survival and recurrence-free survival in colon cancer.11
296323122018Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.66
302448312018Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.48
296323122018Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.66
302448312018Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.48
283027252017Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.14
283027252017Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.14

Citation

Dessen P

ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58191/gene-fusions-explorer/css/template-nav.css